Т-allele of AMPD1 gene limits competitive success in sambo

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Teoriya i praktika fizicheskoy kultury №6 2016, pp.38-41

UDC 796.01:612

PhD E.A. Bondareva1,2
Dr.Biol., Professor E.Z. Godina1, 2
Member-correspondent of RAE, Dr.Hab., Professor A.N. Bleer2
1Research Institute and Museum of Anthropology, Lomonosov Moscow State University, Moscow
2Russian State University of Physical Culture, Sport, Youth and Tourism (GTSOLIFK), Moscow

e-mail: egodina11@gmail.com

Associations between С34Т polymorphism of adenosine monophosphate deaminase 1 (AMPD1) and competitive success in sambo combat were studied. 318 males aged 18-30 years of Russian ethnicity took part in the research. Among them – 92 non-athletes (reference group) and 226 sambo wrestlers. Buccal smears were taken as a biological material for the DNA extraction. The genotyping was performed at the premises of the “LITEX” Laboratory (Moscow, Russia). Some decrease of the homozygous genotype TT frequency was found in the study group (1,3% vs 2,2%). However, the differences were not statistically significant (χ2=1,36 p=,50). Non-random differences (χ2 =12,9 p=,04) were found in the subsample of athletes who showed the worst results in the competition, while among those with average results as well as among winners, no carriers of the given genotype were found.
Basing on these results, it can be assumed that a mutant T-allele of the adenosine monophosphate deaminase 1 gene limits competitive success in sambo wrestlers. Thus, the presence of two T-alleles (AMPD1*TТ) in an athlete’s genotype can be considered as a factor of negative influence on competition results in sambo, when compared with the carriers of two original C-alleles (AMPD1*СС).

Keywords: sport anthropology, sambo combat, AMPD1 gene, sports selection, sports and competitive success.

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Received 31.03.2016 г.