Dr. Biol., Associate Professor S.Yu. Zavalishina¹
Dr. Hab., Associate Professor A.S. Makhov^1
1Russian State Social University, Moscow

Keywords: boys, running, physical activity, erythrocytes, cell surface.

Introduction. Low muscle activity often leads even in young people to the development of many diseases and the development of their complications [1]. An important mechanism of this is considered to be the development of a number of hematological disorders that occur in conditions of low muscle activity [2]. Of great interest is the clarification of the dynamics of the rheological properties of erythrocytes in physically untrained young men who have started regular physical training.
The aim of the study was to evaluate the properties of red blood cells in physically inactive young men who started regular jogging.
Methodology and organization of the study. 28 young men aged 17-18, who previously had low physical activity and started regular one-hour jogging at an arbitrary pace at least four times a week, were examined. The observation of them lasted six months. The control group consisted of 22 young men aged 17-18 who had been jogging for at least three years regularly at least four times a week for an hour. Hematological and statistical methods of investigation were applied.
The results of the study and their discussion. When taken under observation, thromboxane B2 was increased by 25.6% in the blood of those with low motor activity and the level of 6‑keto-prostaglandin F1 α was reduced by 13.8%. Initially, the amounts of cholesterol in their erythrocytes were increased by 14.2%, acylhydroperoxide by 30.6% and little new dialdehyde by 32.4%. At the same time, the level of total phospholipids in their erythrocytes was reduced by 13.9%. In the blood of those who had low fitness before the start of jogging, the level of discoid erythrocytes was reduced by 14.5% with a significant excess of the control level in the number of reversibly and irreversibly altered erythrocytes.
In the conditions of regular jogging in the blood of the observation group, the imbalance of arachidonic acid metabolites was eliminated, the lipid composition of erythrocytes was normalized and the content of lipid peroxidation products in them was reduced to the control level. Against the background of regular jogging in the blood of these young men, the level of red blood cells‑discocytes increased by 12.2% and the content of reversibly altered red blood cells decreased by 18.2%, irreversibly transformed red blood cells by 5.4 times, which ensured the normalization of these indicators.
Conclusion. The beginning of systematic running exercises optimizes the biochemical and rheological characteristics of erythrocytes in previously physically inactive young men. This greatly facilitates their microcirculation processes, enhances metabolism and contributes to their overall recovery. The achieved results give grounds to widely recommend physically untrained young men to increase their physical activity by starting running workouts.

Literature

1. Medvedev I.N. Functional features of the heart in athletes / I.N. Medvedev, E.S. Kachenkova // Theory and practice of physics . culture. – 2021. No. 8. – pp. 20-21.
2. Medvedev I.N., Gusev A.V., Malyshev A.V., Mikhailova O.D., Garina E.V., Petina E. Sh., Tagirova N.Dz. Influence of the Experience of Health-Improving Jogging on the Level of Functional Activity of Platelets in Men of the Second Mature Age. Systematic Reviews in Pharmacy. 2020; 11(8): рр. 432-438.